Synthesis of Mannich Bases of Benzimidazole as Possible Antiviral Agents
Corresponding Author(s) : M.S. Shinegare
Asian Journal of Chemistry,
Vol. 8 No. 2 (1996): Vol 8 Issue 2
Abstract
The benzimidazolin-2-thione and formaldehyde stirred and
added substituted-2-amino. benzothiazole in presence of traces of
conc. HCI and refluxed for I h. to give 1,3-bis-[substituted amino
benzothiazolyl]-methyl benzimidazolin-2-thione(III) by Mannich
reaction. The antiviral screenings of all compounds were studied
against tobacco mosaic virus (TMV) and cucumber green mottle
mosaic virus (CGMMV) both in vitro and in vivo.
Keywords
Synthesis
Mannich Bases
Benzimidazole
Antiviral Agents
Shinegare, M., Mane, D., Shinde, D., Thore, S., & Bhawsar, S. (2010). Synthesis of Mannich Bases of Benzimidazole as Possible Antiviral Agents. Asian Journal of Chemistry, 8(2), 225–228. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/24051
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