Synthesis, Electro-optical Characteristic and Antimicrobial Efficacy of Some Benzothiazolium Asycyanine Colorants

Abstract

Fourteen new benzothiazolium butadienylene chain substituted

asycyanine colorants have been synthesised by catalytic condensation

of two styryl pbenyl ketones namely 4-dimethylaminostyryl-

4´-nitrophenyl ketone and 4-dimethylaminostyryl-4´-methoxyphenyl

ketone with 2-methyl benzothiazolium methiodide and

2-methyl-6-substituted benzothiazolium methiodides using piperidine

as basic catalyst and ethanolic DMF as solvent. These colorants

were synthesised with the object to study the effects of electron

acceptor and donor substituents at the 4´-position in the chain

β-phenyl nucleus, chain elongation, on visible absorption maxima

and to evaluate their antimicrobial activity. The dyes were found to

exhibit uniform increase of absorption maxima when collated with

analogues having no substituents in the β-phenyl nucleus and the

analogues having vinylene chain. Purified samples were also investigated

in vitro against Staphylococcus aureus and E.fcherichia coli

and some of them were found to be active.