Aqueous Solubility Predictions of Aliphatic Alcohols, Alkyl Substituted Benzoates and Steroids
Corresponding Author(s) : D. Satyanarayana
Asian Journal of Chemistry,
Vol. 9 No. 3 (1997): Vol 9 Issue 3
Abstract
The aqueous solubility data of aliphatic alcohols, alkyl substituted benzoates and steroids was regressed against physico-chemical properties of the solutes. The solubility parameter, molar volume and melting point were used as independent parameters. Three parameter approach yielded good
correlations. The contribution of melting point to the overall correlations
is marginal. It indicates that when functional groups exhibit stronger interactions
with water. the influence of melting point on the aqueous solubility
may be reduced.
Keywords
Aqueous Solubility
Predictions
Aliphatic Alcohols
Alkyl Substituted Benzoates
Steroids
(1)
Satyanarayana, D.; Narayana Charyulu, R.; Nagavi, B. Aqueous Solubility Predictions of Aliphatic Alcohols, Alkyl Substituted Benzoates and Steroids . ajc 2010, 9, 418-426.
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