Synthesis, Spectral and Thermal Studied of Biologically Active Complexes of Lanthanum(III) with N-alkylphenothiazines

Abstract

Six N-alkylphenothiazines have been used to synthesize the complexes

of lanthanum(III) of the general formula [La(L)₂(NO₃)₂]NO₃, (where L =

N-alkylphenothiazine). The complexes have been characterized on the

basis of analytical, spectral, conductometric and thermogravimetric studies.

Spectroscopic studies indicate that two N-alkylphenothiazine ligands and

two nitrate groups are coordinated to the metal in a bidentate fashion

suggesting a coordination number eight around lanthanum. The antibacterial

screenings of all compounds were carried against Escherichia coli,

Staphylococcus aureus, Bacillus subtilis sp. and Salmonella sp. bacteriae.