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Sterols and Other Metabolites from Freshwater Microalga Chlorococcum infusionum (Schrank) Meneghini
Corresponding Author(s) : Consolacion Y. Ragasa
Asian Journal of Chemistry,
Vol. 32 No. 7 (2020): Vol 32 Issue 7
Abstract
Chemical investigation of the dichloromethane extract of Chlorococcum infusionum afforded a mixture of chondrillasterol (1) and 22-dihydrochondrillasterol (2) in a 3:1 ratio as the major sterols, and lutein (3), triacylglycerols (4), fatty acids (5) and hydrocarbons (6) as the minor compounds. The structures of compounds 1 and 2 were elucidated by extensive 1D and 2D NMR spectroscopy, while compounds 3-6 were identified by comparison of their NMR data.
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- G.W. Patterson, Comparative Biochem. Physiol., 47B, 453 (1991).
- T. Akihisa, T. Hori, H. Suzuki, T. Sakoh, T. Yokota and T. Tamura, Phytochemistry, 31, 1769 (1992); https://doi.org/10.1016/0031-9422(92)83144-N
- G.A. Thompson Jr., Biochim. Biophys. Acta, 1302, 17 (1996); https://doi.org/10.1016/0005-2760(96)00045-8
- D. Martin-Creuzburg and P. Merkel, J. Plankton Res., 38, 865 (2016); https://doi.org/10.1093/plankt/fbw034
- S.J. Taipale, M. Hiltunen, K. Vuorio and E. Peltomaa, Front. Plant Sci., 7, 212 (2016); https://doi.org/10.3389/fpls.2016.00212
- M. Piepho, D. Martin-Creuzburg and A. Wacker, PLoS One, 5, e15828 (2010); https://doi.org/10.1371/journal.pone.0015828
- D.C. Wright, L.R. Berg and G.W. Patterson, Phytochemistry, 19, 783 (1980); https://doi.org/10.1016/0031-9422(80)85110-7
- X. Luo, P. Su and W. Zhang, Mar. Drugs, 13, 4231 (2015); https://doi.org/10.3390/md13074231
- P. Kumari, M. Kumar, C.R.K. Reddy and B. Jha, Algal Lipids, Fatty Acids and Sterols, In: Functional Ingredients from Algae for Foods and Nutraceuticals, Woodhead Publishing Limited, p. 88 (2013).
- B. Hernandez-Carlos and M. Gamboa-Angulo, Phytochem. Rev., 10, 261 (2011); https://doi.org/10.1007/s11101-010-9192-y
- A. Harvey, Drug Discov. Today, 5, 294 (2000); https://doi.org/10.1016/S1359-6446(00)01511-7
- T. Iida, T. Ishikawa, T. Tamura and T. Matsumoto, J. Jpn. Oil Chem. Soc., 29, 345 (1980); https://doi.org/10.5650/jos1956.29.345
- S. Seo, A. Uomori, Y. Yoshimura, K. Takeda, H. Seto, Y. Ebizuka, H. Noguchi and U. Sankawa, J. Chem. Soc., Perkin Trans. I, 1969 (1989); https://doi.org/10.1039/P19890001969
- V.D. Ebajo Jr., C.-C. Shen and C.Y. Ragasa, J. Appl. Pharm. Sci., 5, 33 (2015).
- C.Y. Ragasa, O.B. Torres, E. Marasigan and C.-C. Shen, Der Pharma Chem., 6, 229 (2014).
- C.Y. Ragasa, O.B. Torres, J.M.P. Gutierrez, H.P.B.C. Kristiansen and C.-C. Shen, J. Appl. Pharm. Sci., 5, 94 (2015); https://doi.org/10.7324/JAPS.2015.50416
- C.Y. Ragasa, V.D. Ebajo Jr., N. Lazaro-Llanos, R. Brkljaèa and S. Urban, Der Pharma Chem., 7, 473 (2015).
- D.E. James, Am. Biol. Teach., 30, 743 (1968); https://doi.org/10.2307/4442268
- M.A. Borowitzka, Algae Oils for Biofuels: Chemistry, Physiology and Production, In: Single Cell Oils; Microbial and Algal Oils, edn 2, p. 271 (2010).
References
G.W. Patterson, Comparative Biochem. Physiol., 47B, 453 (1991).
T. Akihisa, T. Hori, H. Suzuki, T. Sakoh, T. Yokota and T. Tamura, Phytochemistry, 31, 1769 (1992); https://doi.org/10.1016/0031-9422(92)83144-N
G.A. Thompson Jr., Biochim. Biophys. Acta, 1302, 17 (1996); https://doi.org/10.1016/0005-2760(96)00045-8
D. Martin-Creuzburg and P. Merkel, J. Plankton Res., 38, 865 (2016); https://doi.org/10.1093/plankt/fbw034
S.J. Taipale, M. Hiltunen, K. Vuorio and E. Peltomaa, Front. Plant Sci., 7, 212 (2016); https://doi.org/10.3389/fpls.2016.00212
M. Piepho, D. Martin-Creuzburg and A. Wacker, PLoS One, 5, e15828 (2010); https://doi.org/10.1371/journal.pone.0015828
D.C. Wright, L.R. Berg and G.W. Patterson, Phytochemistry, 19, 783 (1980); https://doi.org/10.1016/0031-9422(80)85110-7
X. Luo, P. Su and W. Zhang, Mar. Drugs, 13, 4231 (2015); https://doi.org/10.3390/md13074231
P. Kumari, M. Kumar, C.R.K. Reddy and B. Jha, Algal Lipids, Fatty Acids and Sterols, In: Functional Ingredients from Algae for Foods and Nutraceuticals, Woodhead Publishing Limited, p. 88 (2013).
B. Hernandez-Carlos and M. Gamboa-Angulo, Phytochem. Rev., 10, 261 (2011); https://doi.org/10.1007/s11101-010-9192-y
A. Harvey, Drug Discov. Today, 5, 294 (2000); https://doi.org/10.1016/S1359-6446(00)01511-7
T. Iida, T. Ishikawa, T. Tamura and T. Matsumoto, J. Jpn. Oil Chem. Soc., 29, 345 (1980); https://doi.org/10.5650/jos1956.29.345
S. Seo, A. Uomori, Y. Yoshimura, K. Takeda, H. Seto, Y. Ebizuka, H. Noguchi and U. Sankawa, J. Chem. Soc., Perkin Trans. I, 1969 (1989); https://doi.org/10.1039/P19890001969
V.D. Ebajo Jr., C.-C. Shen and C.Y. Ragasa, J. Appl. Pharm. Sci., 5, 33 (2015).
C.Y. Ragasa, O.B. Torres, E. Marasigan and C.-C. Shen, Der Pharma Chem., 6, 229 (2014).
C.Y. Ragasa, O.B. Torres, J.M.P. Gutierrez, H.P.B.C. Kristiansen and C.-C. Shen, J. Appl. Pharm. Sci., 5, 94 (2015); https://doi.org/10.7324/JAPS.2015.50416
C.Y. Ragasa, V.D. Ebajo Jr., N. Lazaro-Llanos, R. Brkljaèa and S. Urban, Der Pharma Chem., 7, 473 (2015).
D.E. James, Am. Biol. Teach., 30, 743 (1968); https://doi.org/10.2307/4442268
M.A. Borowitzka, Algae Oils for Biofuels: Chemistry, Physiology and Production, In: Single Cell Oils; Microbial and Algal Oils, edn 2, p. 271 (2010).