Synthesis, Anti-HIV and Anticancer Activities of Some New Formazans

Abstract

1-(Phenyl-3-(2-methyl-4-NN´-bis-2´-cyanoetbyl-aminophenyl)

5-chlorosalicylformazans have been synthesised by first reacting

2-methyl-4-NN´-bis-2´-cyanoethylamino-benzaldehyde with

5-chlorosalicylhydrazide which gave respective acidhydrazone.

The acidhydrazone on treatment with diazotised aromatic amines

in pyridine medium furnished formazans in 30 to 85% yield.

Three derivatives of the formazans have been prepared by the

reaction of the formazans with acylchlorides under Schotten-Baummanm

reaction conditions.