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Vol. 32 No. 7 (2020): Vol 32 Issue 7

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Synthesis, Characterization and Anti-Cancer Studies of Curcumin Diketimines-Heteropolyacid Composites

Bharath Samannan
Department of Chemistry, Sacred Heart College (Autonomous), Tirupattur-635601, India
Jothi Selvam
Department of Chemistry, Sacred Heart College (Autonomous), Tirupattur-635601, India
Jeyabalan Thavasikani
Department of Chemistry, Sacred Heart College (Autonomous), Tirupattur-635601, India

Corresponding Author(s) : Jeyabalan Thavasikani

jayabalandr@gmail.com

Asian Journal of Chemistry, Vol. 32 No. 7 (2020): Vol 32 Issue 7

Abstract

A novel composite of curcumin diketimine (CDK)-heteropolyacid (where HPA = vanadium doped Keggin anion and CDK = curcumin-benzoguanamine) had been synthesized. The hybrid composites were investigated by analytical methods such as elemental analysis, FT-IR, 13C NMR, SEM, EDS, XRD, DSC-TGA, ESR spectral studies and biological activities. Encapsulated hybrid composite also studied (in vitro) against MCF-7 cancer cell lines. ESR results showed that the presence of (V4+) ion nitrogen ligation in the composite. 13C NMR of CDK ligand value of 183.37 and 55.06 ppm corresponds to (2=N) and (O-CH3) may be due to the composites. The morphology of molybdovanadate (HPA) showed a structure of self-assembled round shape of a diameter around 1 μm.

Keywords

Curcumin diketimines Heteropoly acid Hybrid composites Breast Cancer activity MCF-7
Samannan, B., Selvam, J., & Thavasikani, J. (2020). Synthesis, Characterization and Anti-Cancer Studies of Curcumin Diketimines-Heteropolyacid Composites. Asian Journal of Chemistry, 32(7), 1534–1542. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/2374
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References
  1. N.S. Elbialy, J. Adv. Phys., 16, 185 (2019); https://doi.org/10.24297/jap.v16i1.8276
  2. Azizullah, M. Al-Rashida, A. Haider, U. Kortz, S.A. Joshi and J. Iqbal, ChemistrySelect, 3, 1472 (2018); https://doi.org/10.1002/slct.201702253
  3. K. Girish, B. Channu and A.R. Baba, Indian J. Pharm. Sci., 81, 150 (2019); https://doi.org/10.4172/pharmaceutical-sciences.1000491
  4. M. Jalali-Heravi, A.A. Khandar and I. Sheikshoaie, Spectrochim. Acta A Mol. Biomol. Spectrosc., 55, 2537 (1999); https://doi.org/10.1016/S1386-1425(99)00044-X
  5. K. Rurack, J.L. Bricks, G. Reck, R. Radeglia and U. Resch-Genger, J. Phys. Chem., 104, 3087 (2000); https://doi.org/10.1021/jp994269k
  6. Z. Xu, G. Bai and C. Dong, Bioorg. Med. Chem., 13, 5694 (2005); https://doi.org/10.1016/j.bmc.2005.06.023
  7. S. Sumathi, P. Tharmaraj, C.D. Sheela and R. Ebenezer, J. Coord. Chem., 65, 506 (2012); https://doi.org/10.1080/00958972.2012.655727
  8. M. Karimpour, M.A.H. Feizi, M. Mahdavi, B. Krammer, T. Verwanger, F. Najafi and E. Babaei, Phytomedicine, 57, 183 (2019); https://doi.org/10.1016/j.phymed.2018.11.017
  9. R. Duan, Z. Ou, W. Wang, S. Chen and X. Zhou, Spectrochim. Acta A Mol. Biomol. Spectrosc., 151, 64 (2015); https://doi.org/10.1016/j.saa.2015.05.063
  10. F. Shen, Z.B. Ou, Y.J. Liu, W. Liu, B.-F. Wang, Z.-W. Mao and X.-Y. Le, Inorg. Chim. Acta, 465, 1 (2017); https://doi.org/10.1016/j.ica.2017.05.030
  11. M. Croce, S. Conti, C. Maake and G.R. Patzke, Eur. J. Inorg. Chem., 2019, 348 (2019); https://doi.org/10.1002/ejic.201800268
  12. H. Cao, C. Li, W. Qi, X. Meng, R. Tian, Y. Qi, W. Yang and J. Li, PLoS One, 12, e0181018 (2017); https://doi.org/10.1371/journal.pone.0181018
  13. S. Wang and G.Y. Yang, Chem. Rev., 115, 4893 (2015); https://doi.org/10.1021/cr500390v
  14. J. Kafawein, H.K. Juwhari and M.A. Al-Damen, J. Cluster Sci., 26, 1683 (2015); https://doi.org/10.1007/s10876-015-0867-9
  15. S. Bharath, S. Jothi, P. Peter and T. Jeyabalan, Int. J. Recent Scient. Res., 9, 23480 (2018).
  16. J. Arichi, M.M. Pereira, P.M. Esteves and B. Louis, Solid State Sci., 12, 1866 (2010); https://doi.org/10.1016/j.solidstatesciences.2010.01.022
  17. K. Shakeela, G. Silpa, S.K. Rayala and G.R. Rao, J. Chem. Sci., 130, 107 (2018); https://doi.org/10.1007/s12039-018-1501-9
  18. K. Sivakumar, G. Parinamachivayam, M.M. Krishnan, S. Chakravarty and A. Bharathi, Spectrochim. Acta A Mol. Biomol. Spectrosc., 200, 212 (2018); https://doi.org/10.1016/j.saa.2018.04.034
  19. I. Kaminker, H. Goldberg, R. Neumann and D. Goldfarb, Chem. Eur. J., 16, 10014 (2010); https://doi.org/10.1002/chem.201000944
  20. K. Geetha, A. Athira and N.J. Alummoottil, Int. J. Pharm. Pharm. Sci., 6, 171 (2014).
  21. X. Liao, D. Wu, B. Geng, S. Lu and Y. Yao, RSC Adv., 7, 48454 (2017); https://doi.org/10.1039/C7RA08448J
  22. W. Li, J. Xu, X. He, J. Zhang, E. Zong, X. Liu and S. Fu, IOP Conf. Series Mater. Sci. Eng., 207, 012015 (2017); https://doi.org/10.1088/1757-899X/207/1/012015
  23. S.S. Hosseinyzade, F.M. Zonoz and B. Bahramian, Catal. Lett., 148, 1324 (2018); https://doi.org/10.1007/s10562-018-2354-z
  24. R. Kitture, S. Ghosh, P.A. More, K. Date, S. Gaware, S. Datar, B.A. Chopade and S.N. Kale, J. Nanosci. Nanotechnol., 15, 4039 (2015); https://doi.org/10.1166/jnn.2015.10322
  25. N. Kanagathara, N. Sivakumar, K. Gayathri, N.G. Renganathan, P. Krishnan, S. Gunasekaran and G. Anbalagan, Proc. Indian Nat. Sci. Acad., 79, 467 (2013).
  26. A.P. Zambre, V.M. Kulkarni, S. Padhye, S.K. Sandur and B.B. Aggarwal, Bioorg. Med. Chem., 14, 7196 (2006); https://doi.org/10.1016/j.bmc.2006.06.056
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