Studies on Arylhydrazones Part XV: Reduction of Ethyl 2,3-dioxo-2-o-nitrophenylhydrazono Butyrate

Abstract

Reduction of ethyl 2,3-dioxo-2-o-nitrophenylhydrazono butyrate wascarried out using various reducing agents such as FeSO₄ /NH₃, NH₄Cl /Zndust, Sn/HCl,  Zn/CH₃COOH,  Zn/HCl,  SnCI₂/HCI,  H₂S/alc. NH₃ andsodium dithionite. In all the above methods of reduction, the reductionwith Na₂S₂O₄ was proved to be an efficient and excellent method due toeasier process, a much better yield of amino compound in spite of theformation of the sodium salt of o-sulphamic acid to a greater extent.Reduction product (amino compound) was isolated and characterised byphysical and spectral methods. Finally the amino compound was establishedby forming the N-formyl and N-acetyl derivatives from the sodiumsalt of o-sulphamic acid and the various condensation products (anils) withdifferent aldehydes.