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Vol. 31 No. 5 (2019): Vol 31 Issue 5

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Microwave Assisted Synthesis of 1,5-Benzothiazepines Using Greener Reaction Medium

https://doi.org/10.14233/ajchem.2019.21716
Sanjay S. Kotalwar
Department of Chemistry, Lal Bahadur Shastri Senior College, Partur-431501, India
Amol D. Kale
Department of Chemistry, Swami Vivekanand Senior College, Mantha-431504, India
Ram B. Kohire
Department of Chemistry, Swami Vivekanand Senior College, Mantha-431504, India
Vasant B. Jagrut
Department of Chemistry, Swami Vivekanand Senior College, Mantha-431504, India

Corresponding Author(s) : Vasant B. Jagrut

jagrutvb@gmail.com

Asian Journal of Chemistry, Vol. 31 No. 5 (2019): Vol 31 Issue 5

Abstract

An efficient and eco-friendly synthesis of 1,5-benzothiazepines has been developed by the reaction of various 2-propen-1-ones with 2-aminothiophenol using microwave irradiation in greener reaction medium, glycerol. The clean reaction conditions, shorter reaction time, high yields and non-toxic, biodegradable reaction medium manufactured from renewable sources are unique features of this method.

Keywords

1,5-Benzothiazepines Chalcone Glycerol Microwave Green synthesis
Kotalwar, S. S., Kale, A. D., Kohire, R. B., & Jagrut, V. B. (2019). Microwave Assisted Synthesis of 1,5-Benzothiazepines Using Greener Reaction Medium. Asian Journal of Chemistry, 31(5), 993–996. https://doi.org/10.14233/ajchem.2019.21716
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