Synthesis of Mono and Unsymmetrical Di-and Triesters and Amides by High Dilution Technique

Abstract

Synthesis of a number of useful mono and unsymmetrical diamides, di-and

triesters (1-18) from diamines or di- and trihydroxy compounds has

been achieved by chemoselective derivatisation of diamines and diols or

triols by application of high dilution technique. This method avoids the

conventional use of a large excess of one component to the other and also

allows the preparation of differentialy protected trihydric alcohol like

glycerol.