Synthesis and Antimicrobial Activity of Newly Synthesized Substituted 3-flavanol

Abstract

2´-Hydroxy-5´-chlorochalcone and its derivatives react with

H₂O₂ in presence of NaOH to give 6-chloro-3-flavanol and its

derivatives. These synthesised compounds were tested against

test organisms Staphylococcus aurecus, Staphylococous pyrogens,

S. agalactiae, S. faecalis, Corynebacterium ulcerans, C.

minutissimum, Clostridum septicum, Clostridium tetani and

Escherichia coli. The % MIC values were determined by using

serial dilution method.