Thermodynamic Studies of Interaction Between Cetylrimethyl Ammonium Bromide and Lysozyme Using Potentiometric Techniques

Abstract

The interaction between cetyltrimethyl ammonium bromide and
lysozyme was studied by a potentiometric method using a surfactant-
selective electrode. The binding isotherms of the interaction
between cetyl trimethyl ammonium bromide were measured for
different conditions and show a concentration dependence attributable
to aggregation of the lysozyme-surfactant complexes. The
binding isotherms are discussed in terms of the binding potential
concept of Wyman and are used to calculate an apparent Gibbs
energy of binding per surfactant cation.