Studies on Effect of Some Medicinal Plants on Pancreatic Lipase Activity using Spectrophotometric Method

Abstract

Forty medicinal plants were studied for their effect on pancreatic
lipase activity. The method involves the prior incubation of enzyme
with 10% w/v aqueous decoction of plant drug. The enzyme activity
was assayed by colorimetry at 710 om. Percentage activation or inhibition
of enzyme by plant extract was calculated by comparing the activity
of pancreatic lipase in presence and absence of plant extract. Results
of studies showed that  Eugenia caryophyllus, Mesua Jerea, Terminalia
belerica, Terminalia chebula, Swertia chirata, Witlzania somnifera have
significant inhibitory effect on the activity of enzyme. Tribulus terrestris
and Picrasma excelsa showed activation of enzyme activity.