Synthesis and Biological Activities of 3-Substitued-1-Tetralone Derivatives: Part-I

Abstract

2-Amino-4,5-dihydronaphtho-[1,2-d]-thiazole was condensed with
salicylaldehyde to get Schiff base, it was reduced and cyclized to get
2H -3-( 4,5-dihydronaphth-[1,2-d]-thiazole)-3,4-dihydro-1,3- benzoxazine.
The Schiff base with DMSO-I₂-H₂SO₄ gave 2H-
3-( 4,5-dihydronaphtho - [1,2-d]-thiazole) - 3,4-dihydro - 1,3-benzoisoxazole.
Synthesis of 6-methoxy methyl naphtho-[1,2-d][1,2,3]-thiazole-
4-carboxylate, 6-methoxynaphtho-[ 1 ,2-d] [1,2,3]-thiazole-
4-hydrazo-carbonyl and 6-methoxynaphtho-[I1,2-d][1,2,3]-thiazole-4-
arylidene hydrazocarbonyl prepared from the starting compound 3-
carbmethoxy-7 -methoxy-1-tetralone.