Issue

Vol. 14 No. 2 (2002): Vol 14 Issue 2

Determination of Indinavir Sulphate by Visible Spectrophotometry

C.S.N. Sarma
Department of Physical, Nuclear and Chemical Oceanography, School of Chemistry, Andhra University, Visakhapatnarn-530 003, India
C. Kamala Sastri
Department of Physical, Nuclear and Chemical Oceanography, School of Chemistry, Andhra University, Visakhapatnarn-530 003, India
C.S.P. Sastri
Department of Physical, Nuclear and Chemical Oceanography, School of Chemistry, Andhra University, Visakhapatnarn-530 003, India

Corresponding Author(s) : C.S.P. Sastri

Asian Journal of Chemistry, Vol. 14 No. 2 (2002): Vol 14 Issue 2

Abstract

Three simple and sensitive visible spectrophotometric methods (M1, M2, M3) are developed for the estimation of Indinavir sulphate (INS) in bulk and dosage forms. They are based on the formation of coloured species with sodium nitroprusside-acetaldehyde (SNP-ACD, method-M1), cobalt thiocyanate (CTC, method-M2) and citric
acid-acetic anhydride (CA-AA, method-M3) reagents exhibiting
maximum absorption at 560, 600, and 560 nm respectively. Methods
M1, M2, M3 obeyed Beer's law limits 0.6–6 μg mL–1, 1.4–15 μg
mL–1 and 1.65–20 μg mL–1 repectively and are statistically
validated. The proposed methods are selective, simple and
economicical for the quantitative determination of Indinavir sulphate.

Keywords

Determination Indinavir Sulphate Visible Spectrophotometry
Sarma, C., Kamala Sastri, C., & Sastri, C. (2010). Determination of Indinavir Sulphate by Visible Spectrophotometry . Asian Journal of Chemistry, 14(2), 691–698. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/22138
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0