Synthesis of 2-Thiophenyl-3-Substituted Phenyl-4-Oxo-5-Substituted Benzylidine Thiazolidine

Abstract

4-Thiazolidinones are known for their antibacterial, antifungal, antithyroid and amoebicidal properties. 2-Thiophenyl-3-substituted phenyl-4-oxo-thiazolidines were condensed with aromatic aldehyde (benzaldehyde, anisaldehyde, salicylaldehyde and 2-nitrobenzaldehyde) to yield 2-thiophenyl-3-subsituted phenyl-4-oxo-5-substituted benzylindine-thiazolidine. The structures of these compounds were confirmed by spectral and chemical data.