UV Spectrophotometric Methods for the Determination of Saquinavir Mesylate and Efavirenz
Corresponding Author(s) : D.G. Sankar
Asian Journal of Chemistry,
Vol. 15 No. 3 (2003): Vol 15 Issue 3
Abstract
Simple and sensitive UV spectrophotometric methods have been
developed for the determination of two anti-HIV drugs, saquinavir
mesylate and efavirenz in bulk and their formulations. Both the
drugs were taken in methanol solution and maximum absorbance
was observed at 239 nm or 247 nm respectively. Beer's law was
obeyed in the concentration of 1.25 to 10 μg/mL for saquinavir
mesylate and 2.5 to 12.5 μg/mL for efavirenz. There is no interference
from any common pharmaceutical additives and diluents.
Keywords
UV spectrophotometric methods
Saquinavir mesylate
Efavirenz
(1)
Sankar, D.; Kumar, J.; Reddy, M. UV Spectrophotometric Methods for the Determination of Saquinavir Mesylate and Efavirenz . ajc 2010, 15, 1856-1858.
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