Synthesis of Some New N-Thio Carbamoyl-3-Methyl-4[2’-{4’-p-subst./unsubst.)-phenyl}thiazolyl hydrazono]-2-Pyrazolin-5-one with Possible Antibacterial Activity
Corresponding Author(s) : Bhupender Singh Rawat
Asian Journal of Chemistry,
Vol. 15 No. 3 (2003): Vol 15 Issue 3
Abstract
Several new N-thio carbamoyl-3-methyl-4-[2’-{4’-p-subst./unsubst.)-phenyl}thiazolyl hydrazono]-2-pyrazolin-5-one (II) have been prepared by reaction of ethyl-2-(2’-aryl hydrazono)-3-oxo-butyrate (I) with thiosemicarbazide in ethylacetoacetate All these synthesized pyrazolines have been screened against a few micro-organisms for antibacterial activity. Compounds were characterized by infrared and NMR spectra.
Keywords
Synthesis
Substituted
Unsubstituted
Pyrazolin-5-one
Antibacterial activity
Singh Rawat, B., & Mehra, S. (2012). Synthesis of Some New N-Thio Carbamoyl-3-Methyl-4[2’-{4’-p-subst./unsubst.)-phenyl}thiazolyl hydrazono]-2-Pyrazolin-5-one with Possible Antibacterial Activity. Asian Journal of Chemistry, 15(3), 1545–1548. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/21836
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