Synthesis and Antibacterial Activity of 2-Phenyl Amino-4-(Aryl Thio Ureido/ Aryl Ureido)-6-[{4´ -(2",4"-Dichloro-5"-Fluoro Phenyl)-6´ - (3",4",5"-Trimethoxy Phenyl) Pyrimidine-2´ -yl}Amino]-s-Triazine

Abstract

Some new s-triazine derivatives have been prepared by the condensation
of aniline and cyanuric chloride giving 2-phenyl amino-4,6-dichloro-s-triazine,
which on reaction with aryl thio ureido/aryl ureido gives 2-phenyl
arnino-4-aryl thio ureidolaryl ureido-6-chloro-s-triazine which on further
reaction with 2-arnino-4-(2',4' -dichloro-5' -fluoro phenyl)-6-(3' ,4' ,5'trimethoxy
phenyl) pyrimidine gives the title compound. The structure of
the product has been characterised by elemental analysIs and spectral data.
The products have been screened for their antibacterial activity against
Staphylococcus aureus and Escherichia coli.