Antibacterial Activity of Lactoperoxidase from Sheep Colostrum

Abstract

Various immune factors of colostrum have been reported to be associated
with antibacterial activity. Therefore investigations were carried out
with a view to examine the antibacterial action of the enzyme
lactoperoxidase from the colostrum of sheep. The lactoperoxidase was
purified from colostrum of sheep using ion exchange chromatography on
C.M Sephadex C-50 and gel filtration chromatography on G-100 (Sigma).
Purified lactoperoxidase was found to have antibacterial action against a
number of disease causing bacteria.