Synthesis and Antibacterial Activity of Chalcone and 2-Amino Pyrimidine and Their Related Compound

Abstract

In the present work some biologically active substituted chalcone prepared
through the reaction of  1-acetyl-3-(4'-nitro phenyl)-5-(4'-methoxy
phenyl)-2-pyrazoline with aldehyde and ethanol to give various chalcone
and biologically active 4-[3'-(4"-nitro phenyl)-5'-(4"-methoxy phenyl)-2'pyrazoline
]-6-aryl substituted-2-amino pyrimidine was prepared from
chalcone, guanidine nitrate and ethanol, which reacts with p-acetyl amino
benzene sulphonyl chloride with dry pyridine; it gives 4-[3'-(4"-nitro phenyl)-
5' -( 4" -methoxy phenyl)-2' -pyrazoline ]-6-aryl substituted-2-( 4' -acetyl
amino benzene sulphonamide).