Synthesis of 5-Oxo-2-Arylamino Thiazol-[4,5-d]-Pyrans
Corresponding Author(s) : A.P. RAJPUT
drapr@rediffmail.com
Asian Journal of Chemistry,
Vol. 15 No. 1 (2003): Vol 15 Issue 1
Abstract
Initially (E)-5-(4-oxo-2-arylamino thiazolyl) acrylic acids (3a-f) were
prepared from 4-oxo-2-arylamino thiazole-5-carboxaldebydes (2a-f) using
Perkin's reaction. The acrylic acids (3a-f) on heating with polyphosphoric
acid (PPA) at 245°C formed intermediates (4a-f) (not isolated) which on
hydrolysis with cold alkali yielded pyrans, (5a-f). The structures of acrylic
acids and pyrans were confirmed by physical as well as chemical methods.
Keywords
Arylamino Thiazol pyrans
Pyrans
RAJPUT, A. (2010). Synthesis of 5-Oxo-2-Arylamino Thiazol-[4,5-d]-Pyrans . Asian Journal of Chemistry, 15(1), 506–508. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/21615
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