Synthesis and Pharmacological Studies of Mixed Ligand Complexes of Lanthanide(III) Ions with Schiff Base and Diphenyl Sulphoxide

Abstract

The present research paper is concerned with the synthesis and antimicrobial

studies of some mixed ligand complexes of certain lanthanide(III)

ions with a Schiff base and diphenyl sulphoxide. They are characterized

on the basis of elemental analysis, molar conductances, molecular mass,

and metal percentage, magnetic moments and spectral investigations

(electronic and infrared spectra). Antimicrobial activity of the complexes

was studied. The complexes conform to the composition [Ln(MDDA)₃-

(DPSO)X₃] where X = NO₃^- or NCS^- [Ln(MDDA)₄(DPSO)X₂]X where

X = CIO₄^-. The Schiff base 4-methoxy-4'(N,N-dimethylamino) diphenyl

azomethine (MDDA) is derived by the condensation of p-anisidine and

p-dimethyl amino benzaldehyde. Both the Schiff base and DPSO act as

neutral monodentate ligands and the complexes appear to be seven-coordinated.

The infrared data suggest coordination of the ligand to the metal

ions in a unidentate fashion through the nitrogen atom of the azomethine

group and oxygen atom of the diphenyl sulphoxide molecule. The antimicrobial

screening of the ligands and their complexes has been carried out

Thermal decompositions were studied by TG and DTG techniques.