Synthesis and Characterization of Some Nickel(II) Complexes with 3-Aryl Substituted Amidinothioureas

Abstract

A series of novel complexes of nickel(II) with the 1-amidino-3-
phenyl thiourea (HPATU), 1-amidino-3-p-tolyl thiourea (HPTATU),
1-amidino-3-p-chlorophenyl thiourea (HPCATU) and 1-amidino-3-
p-anisyl  thiourea (HPAATU) have been prepared and characterized
using elemental analysis, magnetic moment measurements and electronic,
infrared, pmr, mass and X-ray spectroscopic techniques. The
electrochemical behaviour of the complex is followed using cyclic
voltammetry and it is seen that the nickel-sulphur linkage is having
more covalent nature. The complexes are crystalline in nature and
have a tetragonal unit cell and the unit cell parameters have been
calculated from the powder X-ray diffraction pattern. The complexes
are neutral and have a square planar structure. The complexes
were screened for their anti staphylococcal activity by administering
the complexes in liquid culture medium containing S. aureus and
assessed the activity by tuibidimetric method.