Synthesis, Characterization and Antibacterial Activity of Some Schiff Bases of 2-Amino-3-(N-Tolyl Carboxamido)-4,5,6,7-Tetrahydro Benzo(b)Thiophenes
Corresponding Author(s) : J. SARAVANAN
Asian Journal of Chemistry,
Vol. 15 No. 1 (2003): Vol 15 Issue 1
Abstract
2-Amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b)
thiophenes (I-III) were synthesized by Gewald reaction. Later, the
compounds I-III were treated with ten different substituted
arylaldehydes to yield thirty new Schiff bases (I a-j to III a-j).
The compounds were characterized by spectral data and were
screened for antibacterial activity. Some of these Schiff bases exhibited
promising activity.
Keywords
Synthesis
Thiophenes
Antibacterial activity
Schiff Bases
(1)
MOHAN, S.; SARAVANAN, J. Synthesis, Characterization and Antibacterial Activity of Some Schiff Bases of 2-Amino-3-(N-Tolyl Carboxamido)-4,5,6,7-Tetrahydro Benzo(b)Thiophenes . ajc 2010, 15, 67-70.
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