Synthesis, Characterization and Antibacterial Activity of Some Schiff Bases of 2-Amino-3-(N-Tolyl Carboxamido)-4,5,6,7-Tetrahydro Benzo(b)Thiophenes
Corresponding Author(s) : J. SARAVANAN
Asian Journal of Chemistry,
Vol. 15 No. 1 (2003): Vol 15 Issue 1
Abstract
2-Amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b)
thiophenes (I-III) were synthesized by Gewald reaction. Later, the
compounds I-III were treated with ten different substituted
arylaldehydes to yield thirty new Schiff bases (I a-j to III a-j).
The compounds were characterized by spectral data and were
screened for antibacterial activity. Some of these Schiff bases exhibited
promising activity.
Keywords
Synthesis
Thiophenes
Antibacterial activity
Schiff Bases
MOHAN, S., & SARAVANAN, J. (2010). Synthesis, Characterization and Antibacterial Activity of Some Schiff Bases of 2-Amino-3-(N-Tolyl Carboxamido)-4,5,6,7-Tetrahydro Benzo(b)Thiophenes . Asian Journal of Chemistry, 15(1), 67–70. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/21505
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