Isolation of Polyphenolic Constituents from Pods of Cassia marginata Roxb. Hort and Their Biological Activity

Abstract

Phytochemical studies on the pods of Cassia marginata resulted in the isolation of two new polyphenolic glycosides: 5,7-dihydroxy-6-methoxy flavone-4´-o-α-L-rhamnosyl-(1→6)-β-D-glucoside (I) and 5,7-dihydroxy-4´-methoxy flavonol-3-o-α-L-rhamnosyl-(1→2)-o-β-D-glucoside (II). The known glycoside kaempferol-o-β-D-glucoside (III) in addition to kaempferol (IV), kaempferide (V), leucocyanidin (VI) and an anthraquinone derivative, rhein (VII) have also been isolated. The structures of all the isolated compounds were established on the basis of chemical and spectral analysis. The acetone extract has been screened for its antibacterial activity.