Synthesis and Characterization of 3-(2-Hydroxy- 3,4-benzophenyl)-5-aryl-substituted-pyrazolines

Abstract

1-(2-Hydroxy-3,4-benzophenyl)-3-aryl-prop-2-ene-1-ones (0.01 mol) (3a–d) and semicarbazide/thiosemicarbazide/isonicotinic acid hydrazide (0.01 mol) were added to DMF (20 mL) and the mixture was refluxed for about 2 h. The reaction mixture was cooled and diluted with water. The semisolid so obtained was triturated with ethanol to get a solid which was recrystallized from ethanol-acetic acid mixture to obtain titled pyrazolines.