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Isolation of Flaccidine, 3-Sitostenone and β-Sitosterol-3-O-β-D-glucopyranoside from Polygonum hydropiper and Evaluation of their Antimicrobial Activities
Corresponding Author(s) : Ranjit K. Nath
Asian Journal of Chemistry,
Vol. 32 No. 1 (2020): Vol 32 Issue 1
Abstract
Flaccidine, 3-sitostenone and β-sitosterol-3-O-β-D-glucopyranoside were isolated from aerial part of medicinal plant Polygonum hydropiper. These compounds were isolated upon repeat column chromatography, HPTLC, RP-18 reverse phase column of dichloromethane and ethyl acetate fractions of the crude methnolic extract. The structures of the isolated compounds were identified by spectroscopic technique. Antimicrobial activities of these compounds against some of bacteria and phyto-pathogenic fungus have been investigated in this study.
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- R. Sultana, R.K. Nath and R. Khatun, Asian Australas. J. Biosci. Biotechnol., 2, 204 (2017).
- M. Ayaz, M. Junaid, F. Ullah, A. Sadiq, M. Ovais, W. Ahmad, S. Ahmad and A. Zeb, BMC Complemen. Altern. Med., 16, Article number: 502 (2016); https://doi.org/10.1186/s12906-016-1491-4.
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- H. Haraguchi, K. Hashimoto and A. Yagi, J. Agric. Food Chem., 40, 1349 (1992); https://doi.org/10.1021/jf00020a011.
- H. Smolarz, Acta Soc. Bot. Pol., 71, 29 (2014); https://doi.org/10.5586/asbp.2002.004.
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- T. Furuta, Y. Fukuyama and Y. Asakawa, Phytochemistry, 25, 517 (1986); https://doi.org/10.1016/S0031-9422(00)85513-2.
- L. Majhenic, M. Skerget and Z. Knez, Food Chem., 104, 1258 (2007); https://doi.org/10.1016/j.foodchem.2007.01.074.
- Z.F. Peng, D. Strack, A. Baumert, R. Subramaniam, N.K. Goh, T.F. Chia, S.N. Tan and L.S. Chia, Phytochemistry, 62, 219 (2003); https://doi.org/10.1016/S0031-9422(02)00504-6.
- Y. Miyazaki, Biosci. Microbiota Food Health, 35, 69 (2016); https://doi.org/10.12938/bmfh.2015-016.
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- X. Yang, M. Kang, Y. Li, E. Kim, S.M. Kang and Y.J. Jeon, J. Microbiol. Biotechnol., 24, 1346 (2014); https://doi.org/10.4014/jmb.1405.05035.
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- R.K. Nath, T.G. Roy and R.K. Sutradhar, Asian Australas. J. Biosci. Biotechnol., 2, 136 (2017)
References
R. Sultana, R.K. Nath and R. Khatun, Asian Australas. J. Biosci. Biotechnol., 2, 204 (2017).
M. Ayaz, M. Junaid, F. Ullah, A. Sadiq, M. Ovais, W. Ahmad, S. Ahmad and A. Zeb, BMC Complemen. Altern. Med., 16, Article number: 502 (2016); https://doi.org/10.1186/s12906-016-1491-4.
R.C. Cambie, A.C. Grimsdale, P.S. Rutledge and P.D. Woodgate, Aust. J. Chem., 43, 485 (1990); https://doi.org/10.1071/CH9900485.
Y. Fukuyama, T. Sato, Y. Asakawa and T. Takemoto, Phytochemistry, 21, 2895 (1980); https://doi.org/10.1016/0031-9422(80)85063-1.
H. Haraguchi, K. Hashimoto and A. Yagi, J. Agric. Food Chem., 40, 1349 (1992); https://doi.org/10.1021/jf00020a011.
H. Smolarz, Acta Soc. Bot. Pol., 71, 29 (2014); https://doi.org/10.5586/asbp.2002.004.
M. Ayaz, M. Junaid, F. Ullah, A. Sadiq, F. Subhan, M.A. Khan, W. Ahmad, G. Ali, M. Imran and S. Ahmad, Front. Pharmacol., 7, 74 (2016); https://doi.org/10.3389/fphar.2016.00074.
M. Ayaz, M. Junaid, F. Ullah, A. Sadiq, M. Ovais, W. Ahmad, S. Ahmad and A. Zeb, BMC Complement. Altern. Med., 16, 502 (2016); https://doi.org/10.1186/s12906-016-1491-4.
A. Debbab, A.H. Aly and P. Proksch, Fungal Divers., 61, 1 (2013); https://doi.org/10.1007/s13225-013-0243-8.
T. Furuta, Y. Fukuyama and Y. Asakawa, Phytochemistry, 25, 517 (1986); https://doi.org/10.1016/S0031-9422(00)85513-2.
L. Majhenic, M. Skerget and Z. Knez, Food Chem., 104, 1258 (2007); https://doi.org/10.1016/j.foodchem.2007.01.074.
Z.F. Peng, D. Strack, A. Baumert, R. Subramaniam, N.K. Goh, T.F. Chia, S.N. Tan and L.S. Chia, Phytochemistry, 62, 219 (2003); https://doi.org/10.1016/S0031-9422(02)00504-6.
Y. Miyazaki, Biosci. Microbiota Food Health, 35, 69 (2016); https://doi.org/10.12938/bmfh.2015-016.
E. Rahman, S.A. Goni, M.T. Rahman and M. Ahmed, Fitoterapia, 73, 704 (2002); https://doi.org/10.1016/S0367-326X(02)00239-3.
M. Ahmed, B.K. Datta, A.S.S. Rouf and J. Jakupovic, Phytochemistry, 30, 3155 (1991); https://doi.org/10.1016/S0031-9422(00)98279-7.
X. Yang, M. Kang, Y. Li, E. Kim, S.M. Kang and Y.J. Jeon, J. Microbiol. Biotechnol., 24, 1346 (2014); https://doi.org/10.4014/jmb.1405.05035.
K.R. Markham and T.J. Mabry, eds.: J.B. Harbome, T.J. Mabry and H. Mabry, The Flavonoids, Part I, Academic Press: New York, pp. 45-126 (1975).
A. Migliuolo, V. Piccialli and D. Sica, J. Nat. Prod., 53, 1262 (1990); https://doi.org/10.1021/np50071a019.
R. Sultana, R. Hossain, A. Adhikari, Z. Ali, M.I. Choudhary and M.S. Zaman, Nat. Prod. Commun., 10, 641 (2015); https://doi.org/10.1177/1934578X1501000428.
R.K. Nath, T.G. Roy and R.K. Sutradhar, Asian Australas. J. Biosci. Biotechnol., 2, 136 (2017)