Synthesis and Pharmacological Activities of Some Schiff Bases Derived from N,N'-Bis(4-ethoxyphenyl)malonamide
Corresponding Author(s) : Alka Pradhan
Asian Journal of Chemistry,
Vol. 18 No. 4 (2006): Vol 18 Issue 4
Abstract
Series of the Schiff Bases (1a-m) of N,N'-bis(4-ethoxyphenyl) malonamide (1) are synthesized by the condensation reaction between compound 1 and substituted aromatic amines. Compound 1 is obtained by condensation of 4-ethoxy aniline and diethylmalonate. The resulting compounds are characterized by spectral data and evaluated for antihistaminic activity. Most of the compounds have shown interesting biological activity.
Keywords
Synthesis
Schiff bases
Antihistaminic activity
N,N'-bis(4-ethoxyphenyl) malonamide
Pradhan, A., Daw, D., Deshmukh, D., & Tripathi, A. (2010). Synthesis and Pharmacological Activities of Some Schiff Bases Derived from N,N’-Bis(4-ethoxyphenyl)malonamide. Asian Journal of Chemistry, 18(4), 3216–3218. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/20816
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