Synthesis and Antimicrobial Activity of Some New Coumarin Derivatives
Corresponding Author(s) : Y. Rajendra Prasad
dryrp@rediffmail.com
Asian Journal of Chemistry,
Vol. 18 No. 4 (2006): Vol 18 Issue 4
Abstract
5,8-Dihydroxy-6-acetyl-4-methyl coumarin (1) was prepared by the reaction of phloroacetophenone with ethyl acetoacetate using Pechmann condensation. Different Schiff bases (2-5) were then synthesized by the reaction between this compound and various aromatic amines. The resulting Schiff bases were identified by chemical and spectral methods. Some of these compounds possessed significant antimicrobial activity.
Keywords
Phloroacetophenone
Coumarin derivatives
Synthesis
Antimicrobial activity
Rajendra Prasad, Y., Ravi Kumar, P., Ram Babu, P., & Chakradhar, V. (2010). Synthesis and Antimicrobial Activity of Some New Coumarin Derivatives. Asian Journal of Chemistry, 18(4), 3147–3150. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/20775
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