Convenient Acylation of Pyrimidine Derivatives Using Microwave Irradiation
Corresponding Author(s) : A. MOBINIKHALEDI
akbar_mobini@yahoo.com
Asian Journal of Chemistry,
Vol. 19 No. 1 (2007): Vol 19 Issue 1
Abstract
N-Acylated ethyl-6-methyl-4-aryl-2-oxo (or thioxo )-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2a-f) and 6-methyl-4-aryl-2-oxo (or thioxo )-1,2,3,4-tetrahydropyrimidine-5-methylketone (2g-h) were synthesized by the reaction of an appropriate pyrimidine derivative (1) and acetic anyhydride under microwave irradiation. Yields of products following recrystallization from ethanol were of the order of 60-85%.
Keywords
Microwave
Pyrimidine
Carboxylate
Methylketone
MOBINIKHALEDI, A., FORUGHIFAR, N., HABIBI, M., & KALATE, Z. (2010). Convenient Acylation of Pyrimidine Derivatives Using Microwave Irradiation. Asian Journal of Chemistry, 19(1), 219–222. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/20441
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