Synthesis, Characterization and Determination of Partition Coefficient of Some Triazole Derivatives of Coumarins for Their Antimicrobial Activity
Corresponding Author(s) : B.S. JAYASHREE
jesolar2001@yahoo.co.in
Asian Journal of Chemistry,
Vol. 19 No. 1 (2007): Vol 19 Issue 1
Abstract
The triazolo-thiadiazinyl coumarins have been synthesized by the action of 3-bromoacetyl coumarin and substituted triazoles. The synthesized compounds have been characterized by IR, 1H-NMR and mass spectral analysis. An attempt to determine the hydrophobic parameter (partition coefficient) was also established. All the test compounds were screened for their antimicrobial activity by qualitative and quantitative method.
Keywords
Coumarin
Triazole
Thiadiazine
Antimicrobial activity
Partition coefficient
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JAYASHREE, B.; SAHU, A.; SRINIVASA MURTHY, M.; VENUGOPALA, K. Synthesis, Characterization and Determination of Partition Coefficient of Some Triazole Derivatives of Coumarins for Their Antimicrobial Activity. ajc 2010, 19, 73-78.
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