Kinetics and Mechanism of Pd(II) Catalyzed Oxidation of Valine and Leucine by Acidic Solution of Chloramine-T

Abstract

The kinetics of oxidation of amino acid (valine and leucine) by acidic solution of chloramine-T have been studied in the presence of PdCl₂ as catalyst. The order of reaction in chloramine-T and substrate is unity but the acidic medium (H⁺) shows inverse first order. The reaction also shows first order with respect to Pd(II) under experimental conditions. ([H⁺] >> [PdCl₂]). A mechanism involing [Pd(II) - AA] (where AA = amino acid) intermediate complexes is proposed.