Synthesis and Crystal Structure of 4-Cyano-3-fluorophenyl- 3-(4-hexoxy-3-methoxyphenyl)acrylic Acid Ester

Abstract

In present study, 4-cyano-3-fluorophenyl-3-(4-hexoxy-3-methoxyphenyl)acrylic acid ester was synthesized through the esterification of 2-fluoro-4-hydroxybenzonitrile and 3-(4-hexoxy-3-methoxyphenyl)acrylic acid ester (4-hydroxyfurelic acid) using N,N'-dicyclohexyl-carbodiimide (DCC) as esterifying agent. The structure of the this compound was characterized using IR and ¹H NMR spectra and X-ray crystallography. The compound crystallizes in the triclinic system, space group P-1, with cell dimensions of a = 7.461(2), b = 11.781(3), c = 13.801(4) Å, α = 96.153(4), β = 93.117(4), γ = 100.207(5)º, V = 1183.7(6) ų and Z = 1.