Post Coital Antifertility Activity of Nigella sativa

Abstract

The methanolic extract of seeds of Nigella sativa prevented pregnancy in female albino rats when administered orally on days 1-3, 4-5 and 6-7 post coitum, respectively. At a dose of 2 g/kg body weight it inhibited implantations 100%. The preparation also shows significant abortifacient activity inducing foetal resorption in pregnant rats at the dose of 2 g/kg body weight, on days 14-16 post coitum.