Evaluation of CNS Activities of Aerial Parts of Jasminum multiflorum Andr.

Abstract

The ethanol extract of Jasminum multiflorum Andr. (EEJM) was tested for possible pharmacological effects on experimental animals. The extract significantly potentiated the sleeping time of mice induced by standard hypnotics viz., pentobarbitone sodium, diazepam and meprobamate in a dose dependent manner. The extract showed significant analgesic properties as evidenced by the significant reduction in the number of writhes and stretches induced in mice by 1.2 % acetic acid solution. Pretreatment with the extract caused significant protection against pentylene tetrazole induced convulsion. The behavioural studies on mice indicate CNS depressant activity of the ethanol extract of J. multiflorum.