Synthesis of Some Biologically Active 3-Methyl-4- (substituted phenylhydrazono)-2-pyrazolin-5-ones and 2-Isoxazolin-5-ones
Corresponding Author(s) : S.S. RAJPUT
ss_rajput65@rediffmail.com; nitinv@universalstarch.com
Asian Journal of Chemistry,
Vol. 19 No. 6 (2007): Vol 19 Issue 6
Abstract
Diazotized substituted anilines were treated with ethyl aceto acetate to yield ethyl-2-(substituted phenyl) hydrazono-3-oxo butyrates (I). Reaction of I with various ammonia derivatives (PhNHNH2, H2NNH2, H2NOH·HCl) furnished pyrazoline-5-ones, isoxazoline-5 ones. The synthesized compounds have been tested for their biological activity.
Keywords
Synthesis
Biologically active
Pyrazolin-5- ones
2-Isoxazolin-5-ones
(1)
RAJPUT, A.; RAJPUT, S. Synthesis of Some Biologically Active 3-Methyl-4- (substituted Phenylhydrazono)-2-Pyrazolin-5-Ones and 2-Isoxazolin-5-Ones. ajc 2010, 19, 4479-4482.
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