Conformational Analysis of Enantiomers of Chiral Chloroalkanes

Abstract

The pairs of compounds that are nonsuperimposable mirror images called enantiomers. There are several classes of enantiomers that are being studied rather extensively because of their industrial and research importance. 2-Chloropentane, 2-chlorohexane and 2-chloropheptane are the most important chiral enantiomers. Conformational analysis is the study of the energies of different conformations.
Many reactions depend on a molecule's ability to twist
into a particular conformation. Conformational analysis can help to
predict which conformations are favoured and which reactions are
more likely to take place. Here we apply conformational analysis
to these three enantiomers. From these we predict the most stable
conformer. Besides that, the successful interpretations of these compounds
using various parameters of the molecules have been provided.