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Vol. 30 No. 12 (2018): Vol 30 Issue 12

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Optimization of Integration Technology of Field Processing and Processing Crude Drugs of Poria cocos According to Biology Effect and Composition Analyses

https://doi.org/10.14233/ajchem.2018.21551
F.Q. Xu
School of Pharmacy, Anhui University of Chinese Medicine, Hefei City 230012, P.R. China
T.S. Wang
School of Integrated Traditional and Western Medicine, Anhui University of Chinese Medicine, Hefei city 230012, P.R. China
Y. Fang
School of Pharmacy, Anhui University of Chinese Medicine, Hefei City 230012, P.R. China
Q. Huang
School of Pharmacy, Anhui University of Chinese Medicine, Hefei City 230012, P.R. China
D.L. Wu
School of Pharmacy, Anhui University of Chinese Medicine, Hefei City 230012, P.R. China
C.S. Jin
School of Pharmacy, Anhui University of Chinese Medicine, Hefei City 230012, P.R. China

Corresponding Author(s) : D.L. Wu

dlwu7375@sina.com

Asian Journal of Chemistry, Vol. 30 No. 12 (2018): Vol 30 Issue 12

Abstract

In this study, the composition analyses along with the diuretic activity and spleen-tonifying effects were adopted to verify the feasibility of integration technology of field processing and processing crude drugs of Poria cocos. The extractions of PCIT and PCTT of Poria cocos administered to rats. The urinary volume and electrolyte excretion (Na+, K+, Cl–) concentrations were measured in the urine of rats and the serum of amylase, D-xylose, gastrin and vasoactive intestinal peptide levels were determined in the spleen deficiency of rats. The PCIT and PCTT could increase the urinary and Na+, Cl– excretion, the diuretic effect of PCIT was rapider than that of PCTT. The PCIT and PCTT would improve the symptoms of spleen deficiency, the levels of serum amylase, D-xylose, gastrin and vasoactive intestinal peptide tended to be normal in the experiment. The results proved that there was no obvious difference of the substances and the effects on diuretic and spleen-tonifying between the integration technology and traditional technology. The technology of integration of field processing and processing crude drugs is feasible for the production of P. cocos.

Keywords

Poria cocos Crude drugs HPLC analysis Diuretic Spleen-tonifying
Xu, F., Wang, T., Fang, Y., Huang, Q., Wu, D., & Jin, C. (2018). Optimization of Integration Technology of Field Processing and Processing Crude Drugs of Poria cocos According to Biology Effect and Composition Analyses. Asian Journal of Chemistry, 30(12), 2699–2703. https://doi.org/10.14233/ajchem.2018.21551
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