Effect of the Substituent in the Benzylation of Piperazine
Corresponding Author(s) : P. MANIKYAMBA
mani_prerepa@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 1 (2008): Vol 20 Issue 1
Abstract
The reaction between piperazine and substituted benzyl bromides was studied in methanol medium and the second order rate constants were determined. Correlation of log k with Hammett's substituent constant resulted in a non linear plot. This non linearity was attributed to the operation of substituent effect on two steps of the reaction scheme to different extents.
Keywords
Piperazine
Substituent effect
Hammett's equation
Reaction constant
Nucleophile
Kinetics
(1)
RANGA REDDY, S.; MANIKYAMBA, P. Effect of the Substituent in the Benzylation of Piperazine. ajc 2010, 20, 195-199.
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