Synthesis of Biologically Active 1-[2-(2-Methyl- 5-nitroimidazol-1-yl)acetyl]-3-substituted Phenyl-4-carbaldehyde-1H-pyrazoles
Corresponding Author(s) : FREDDY H. HAVALDAR
drfreddy_1@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 1 (2008): Vol 20 Issue 1
Abstract
1-[2-(2-Methyl-5-nitroimidazol-1-yl)acetyl]-3-substituted phenyl- 4-carbaldehyde-1H-pyrazoles (4a-e) have been synthesized by the cyclization of (2-methyl-5-nitroimidazol-1-yl)acetic acid (1-substituted phenylethylidine)hydrazides (3a-e) with phosphorous oxychloride in N,N-dimethylformamide. The pyrazoles have been characterized on the basis of analytical and spectral data and screened for biological activity.
Keywords
Synthesis
Pyrazoles
Antibacterial and Antifungal activity
H. HAVALDAR, F., & R. PATIL, A. (2010). Synthesis of Biologically Active 1-[2-(2-Methyl- 5-nitroimidazol-1-yl)acetyl]-3-substituted Phenyl-4-carbaldehyde-1H-pyrazoles. Asian Journal of Chemistry, 20(1), 97–101. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/19349
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