Synthesis and Evaluation of Antioxidant Activity of 6-Methoxy-2H-chromenes
Corresponding Author(s) : ALIREZA FOROUMADI
aforoumadi @tums.ac.ir
Asian Journal of Chemistry,
Vol. 20 No. 3 (2008): Vol 20 Issue 3
Abstract
3-(6-Methoxy-2H-chromen-3-yl)-1-phenyl prop-2-en-1-one and 1-(6-methoxy-2H-chromen-3-yl)-3-phenyl prop-2-en-1-one were synthesized by condensation of 6-methoxy-2H-chromen-3-carbaldehyde or 1-(6-methoxy-2H-chromen-3-yl)ethanone with acetophenone or benzaldehyde, respectively. The synthesized chalcones were evaluated for their antioxidant activity using ferric reducing antioxidant power (FRAP) and DPPH free radical scavenging methods. Both compounds showed antioxidant activity, in comparison with trolox.
Keywords
Antioxidant
Chromene
Synthesis
DPPH & Ferric reducing antioxidant power assay
(1)
SORKHI, M.; FOROUZANI, M.; DEHGHAN, G.; ABDOLLAHI, M.; SHAFIEE, A.; FOROUMADI, A. Synthesis and Evaluation of Antioxidant Activity of 6-Methoxy-2H-Chromenes. ajc 2010, 20, 2151-2155.
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