Quantitative Estimation of Naproxen in Bulk Sample and Tablet Formulation Using Niacinamide as Hydrotropic Solubilizing Agent
Corresponding Author(s) : R.K. Maheshwari
rkrkmaheshwari@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 6 (2008): Vol 20 Issue 6
Abstract
In the present investigation, 2.0 M niacinamide (an economic solubilizing agent) was employed to solubilize poorly water-soluble antiinflammatory drug, naproxen for its titrimetric analysis. The proposed method is new, environmentally friendly, accurate and reproducible. Accuracy, reproducibility and precision of the proposed method were validated statistically.
Keywords
Hydrotropy
Naproxen
Niacinamide
Titrimetry
(1)
Maheshwari, R.; Dubey, A. Quantitative Estimation of Naproxen in Bulk Sample and Tablet Formulation Using Niacinamide As Hydrotropic Solubilizing Agent. ajc 2010, 20, 4225-4228.
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