Oxidative Deoximation of 3-Alkyl Substituted 2,6-Diphenyl Piperidin-4-one Oximes by Pyridinium Fluorochromate: A Kinetic Study
Corresponding Author(s) : K. Tharini
tharini71@yahoo.co.in
Asian Journal of Chemistry,
Vol. 21 No. 1 (2009): Vol 21 Issue 1
Abstract
The oxidation of oximes of 2,6-diphenyl piperidin-4-one and various alkyl substituted 2,6-diphenyl piperidin-4-one by pyridinium fluorochromate (PFC) has been studied. The reaction follows first order each in [PFC] and [oxime]. The reactivity sequence observed is 3-H > 3-Me > 3-Et > 3,3-dime > 3-ipr which has been rationalized on the basis of steric crowding by the substituents.
Keywords
Piperidone oximes
Kinetics
Oxidation
Pyridinium fluorochromate
Mechanism
Tharini, K., Jani Bai, T., & Lakshmi, M. (2010). Oxidative Deoximation of 3-Alkyl Substituted 2,6-Diphenyl Piperidin-4-one Oximes by Pyridinium Fluorochromate: A Kinetic Study. Asian Journal of Chemistry, 21(1), 257–262. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/18919
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