Synthesis of Some 4'-Amino Chalcones and their Antiinflammatory and Antimicrobial Activity

Y. Rajendra Prasad; A. Srinivasa Rao; R. Rambabu

Issue

Vol. 21 No. 2 (2009): Vol 21 Issue 2

Issue Published : October 17, 2008

Synthesis of Some 4'-Amino Chalcones and their Antiinflammatory and Antimicrobial Activity

Y. Rajendra Prasad

Pharmaceutical Chemistry Division, AU College of Pharmaceutical SciencesAndhra University, Visakhapatnam-530 003, India

A. Srinivasa Rao

Pharmaceutical Chemistry Division, AU College of Pharmaceutical SciencesAndhra University, Visakhapatnam-530 003, India

R. Rambabu

Pharmaceutical Chemistry Division, AU College of Pharmaceutical SciencesAndhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : Y. Rajendra Prasad

dryejella@yahoo.co.in

Asian Journal of Chemistry, Vol. 21 No. 2 (2009): Vol 21 Issue 2
Article Published : March 30, 2010

Abstract

A series of some 4'-amino chalcones were synthesized by Claisen- Schmidt condensation of 4-amino acetophenone with various substituted aromatic aldehydes. The synthesized chalcones were characterized by IR, ¹H NMR and elemental analyses. When these chalcones (3a-h) were evaluated for antiinflammatory, antibacterial and antifungal activities, some of them found to possess significant biological activity when compared to standard drugs.

Keywords

Chalcone Synthesis Antiinflammatory Antimicrobial activity

Rajendra Prasad, Y., Srinivasa Rao, A., & Rambabu, R. (2010). Synthesis of Some 4’-Amino Chalcones and their Antiinflammatory and Antimicrobial Activity. Asian Journal of Chemistry, 21(2), 907–914. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/18769

Issue

Vol. 21 No. 2 (2009): Vol 21 Issue 2

Synthesis of Some 4'-Amino Chalcones and their Antiinflammatory and Antimicrobial Activity

Corresponding Author(s) : Y. Rajendra Prasad

Abstract

Keywords

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