Mechanism of Hydrolysis of Mono-2-chloro Aniline Phosphate via Conjugate Acid Species

Abstract

The kinetic study of mono-2-chloro aniline phosphate is carried out in acid medium from 0.1 to 7.0 mol dm^-3 at 50 ºC. The acid log rate profile has a rate maximum at 4.0 mol dm^-3. The lowering in rate after 4.0 mol dm^-3 may be attributed to the lowering in concentration of the water activity or due to positive effect of ionic strength. Ionic strength data exhibit different contribution of neutral species. The observed rates were found in close agreement with the estimated theoretical rates derived from the second empirical term of Debye-Huckel equation. The study of ionic strength, temperature, solvent is provided to identify the reactive species and molecularity. Bimolecular behaviour has been decided by the Arrhenius parameters, Zucker-Hammett hypothesis, Bunnett & Bunnett-Olsen's parameters. The phosphate monoester involves P-N bond fission which is strengthened by comparative kinetic rate data.