Copyright (c) 2014 AJC
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A New Phenolic Amide from Stems of Cassia fistula and Their Anti-Tobacco Mosaic Virus Activities
Corresponding Author(s) : Yanqing Ye
Asian Journal of Chemistry,
Vol. 26 No. 18 (2014): Vol 26 Issue 18
Abstract
A new phenolic amide, (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]-prop-2-enamide (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity and it exhibit potential anti-TMV activity with inhibition rates of 16.2 %.
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References
V. Duraipandiyan and S. Ignacimuthu, J. Ethnopharmacol., 112, 590 (2007); doi:10.1016/j.jep.2007.04.008.
S. Rajan, D.S. Baburaj, M. Sethuraman and S. Parimala, Ethnobotany, 6, 19 (2001).
J. Ma, L.X. Zhang and Y.H. Guan, Chin. J. Ethnomed. Ethnopharm, 5, 178 (2004).
K.A. Abo, A.A. Adeyemi and A.O. Sobowale, Afr. J. Med. Med. Sci., 30, 9 (2001).
S. Aurapa and G. Wandee, Int. J. Biomed. Pharm. Sci, 3, 42 (2009).
P. Sartorelli, S.P. Andrade, M.S. Melhem, F.O. Prado and A.G. Tempone, Phytother. Res., 21, 644 (2007); doi:10.1002/ptr.2131.
Y.H. Kuo, P.H. Lee and Y.S. Wein, J. Nat. Prod., 65, 1165 (2002); doi:10.1021/np020003k.
S.L. Jothy, Z. Zakaria, Y. Chen, Y.L. Lau, L.Y. Latha, L.N. Shin and S. Sasidharan, Molecules, 16, 7583 (2011); doi:10.3390/molecules16097583.
W. Zhao, X.Y. Zeng, T. Zhang, L. Wang, G.Y. Yang, Y.K. Chen, Q.F. Hu and M.M. Miao, Phytochem. Lett., 6, 179 (2013); doi:10.1016/j.phytol.2012.12.006.
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