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Electrochemical Behaviour and Analysis of Obidoxime in Pharmaceutical Formulations by Voltammetric Techniques
Corresponding Author(s) : Y.V. Rami Reddy
Asian Journal of Chemistry,
Vol. 26 No. 18 (2014): Vol 26 Issue 18
Abstract
The electrochemical behaviour of obidoxime was studied by employing D.C. polarography, cyclic voltammetry and differential pulse polarography in universal buffers of pH ranging from 2.0-12.0. The kinetic parameters, such as transfer coefficients, diffusion coefficients and heterogeneous forward rate constant values were evaluated by employing these techniques. Differential pulse polarography was employed for the estimation of obidoxime in selected pharmaceutical formulations.
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- Z. Binenfeld, A. Deljac, M. Knez'evic and Lj. Pavlov, Acta Pharm. Jugosl., 31, 5 (1981).
- N.D. Brown, L.L. Hall, H.K. Sleeman, B.P. Doctor and G.E. Demaree, J. Chromatogr. A, 148, 453 (1978); doi:10.1016/S0021-9673(00)85305-4.
- J.G. Clement and P.A. Lockwood, Toxicol. Appl. Pharmacol., 64, 140 (1982); doi:10.1016/0041-008X(82)90332-5.
- M. Maksimovic, D. Pantelic, V. Kovac’evic and Z. Binenfeld, Acta Pharm. Jugosl., 37, 227 (1987).
- J. Bajgar, Adv. Clin. Chem., 38, 151 (2004); doi:10.1016/S0065-2423(04)38006-6.
- C.L. Barthold and J.G. Schier, Crit. Care Clin., 21, 673 (2005); doi:10.1016/j.ccc.2005.05.010.
- F. Ekstrom, A. Hornberg, E. Artursson, L.G. Hammarstrom, G. Schneider and Y.P. Pang, PLoS ONE, 4, e5957 (2009); doi:10.1371/journal.pone.0005957.
- B. Sanson, F. Nachon, J.P. Colletier, M.T. Froment, L. Toker, H.M. Greenblatt, J.L. Sussman, Y. Ashani, P. Masson, I. Silman and M. Weik, J. Med. Chem., 52, 7593 (2009); doi:10.1021/jm900433t.
- M. Pohanka, L. Novotny, J. Zdarova-Karasova, H. Bandouchova, F. Zemek, M. Hrabinova, J. Misik, K. Kuca, J. Bajgar, O. Zitka, N. Cernei, R. Kizek and J. Pikula, Environ. Toxicol. Pharmacol., 32, 75 (2011); doi:10.1016/j.etap.2011.03.014.
- J. Kassa, J. Toxicol. Clin. Toxicol., 40, 803 (2002); doi:10.1081/CLT-120015840.
- J. Kassa and G. Krejeova, Pharmacol. Toxicol., 92, 258 (2003); doi:10.1034/j.1600-0773.2003.920602.x.
References
Z. Binenfeld, A. Deljac, M. Knez'evic and Lj. Pavlov, Acta Pharm. Jugosl., 31, 5 (1981).
N.D. Brown, L.L. Hall, H.K. Sleeman, B.P. Doctor and G.E. Demaree, J. Chromatogr. A, 148, 453 (1978); doi:10.1016/S0021-9673(00)85305-4.
J.G. Clement and P.A. Lockwood, Toxicol. Appl. Pharmacol., 64, 140 (1982); doi:10.1016/0041-008X(82)90332-5.
M. Maksimovic, D. Pantelic, V. Kovac’evic and Z. Binenfeld, Acta Pharm. Jugosl., 37, 227 (1987).
J. Bajgar, Adv. Clin. Chem., 38, 151 (2004); doi:10.1016/S0065-2423(04)38006-6.
C.L. Barthold and J.G. Schier, Crit. Care Clin., 21, 673 (2005); doi:10.1016/j.ccc.2005.05.010.
F. Ekstrom, A. Hornberg, E. Artursson, L.G. Hammarstrom, G. Schneider and Y.P. Pang, PLoS ONE, 4, e5957 (2009); doi:10.1371/journal.pone.0005957.
B. Sanson, F. Nachon, J.P. Colletier, M.T. Froment, L. Toker, H.M. Greenblatt, J.L. Sussman, Y. Ashani, P. Masson, I. Silman and M. Weik, J. Med. Chem., 52, 7593 (2009); doi:10.1021/jm900433t.
M. Pohanka, L. Novotny, J. Zdarova-Karasova, H. Bandouchova, F. Zemek, M. Hrabinova, J. Misik, K. Kuca, J. Bajgar, O. Zitka, N. Cernei, R. Kizek and J. Pikula, Environ. Toxicol. Pharmacol., 32, 75 (2011); doi:10.1016/j.etap.2011.03.014.
J. Kassa, J. Toxicol. Clin. Toxicol., 40, 803 (2002); doi:10.1081/CLT-120015840.
J. Kassa and G. Krejeova, Pharmacol. Toxicol., 92, 258 (2003); doi:10.1034/j.1600-0773.2003.920602.x.