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Vol. 26 No. 18 (2014): Vol 26 Issue 18

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A Green Approach for the Synthesis of 1-Methyl-2-(alkylthio)-1H-benzimidazoles

https://doi.org/10.14233/ajchem.2014.16419
S. Srinivas Rao
Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India
Ch. Venkata Ramana Reddy
Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India
P.K. Dubey
Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India

Corresponding Author(s) : S. Srinivas Rao

seenu604@gmail.com; cnu604@gmail.com

Asian Journal of Chemistry, Vol. 26 No. 18 (2014): Vol 26 Issue 18

Abstract

A green approach for the synthesis of 1-methyl-2-(alkylthio)-1H-benzimidazoles 6 (R1 = CH3, C2H5, CH2Ph) under, different conditions has been developed from N-methyl-2-mercaptobenzimidazole (i.e. CH3) 5 by reaction with an alkylating agent by physical grinding or by using green solvent like PEG-600 or by using micro-wave irradiation technique.

Keywords

Green synthesis Grinding Microwave N-methyl-2-chlorobenzimidazole Benzimidazole N-alkyl-2-mercaptobenzimidazole
Srinivas Rao, S., Venkata Ramana Reddy, C., & Dubey, P. (2014). A Green Approach for the Synthesis of 1-Methyl-2-(alkylthio)-1H-benzimidazoles. Asian Journal of Chemistry, 26(18), 5995–5997. https://doi.org/10.14233/ajchem.2014.16419
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