Copyright (c) 2018 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Synthesis of Graphene Oxide Electrode for Paracetamol Analysis by Cyclic Voltammetry
Corresponding Author(s) : Pirim Setiarso
Asian Journal of Chemistry,
Vol. 30 No. 10 (2018): Vol 30 Issue 10, 2018
Abstract
In this study, graphene oxide was made by using improved method of Hummer for paracetamol detection by cyclic voltammetry. The main reason for using graphene oxide electrode for paracetamol detection is the conductive nature of graphene oxide. The cathodic current peak in the graphene oxide electrode has a more sensitive value than the carbon paste electrode. Paracetamol detection of cyclic voltammetric detection has several factors used to accurately detect paracetamol. Factors that can affect the electrode composition, the pH of the solution, the deposition time and the scan rate. In this study, paracetamol detection using graphene oxide electrode has the optimum electrode composition in the ratio of graphene oxide with paraffin 8:2. The pH of optimum solution for detection of paracetamol is 6, 5-second deposition time and scan rate 200 mV/s. Graphene oxide electrode has a detection limit of up to 0.494 ppm or 0.00327 mM (3.27 μM) with recovery 99.615 %. The proposed sensor shows good selectivity, sensitivity, stable repetition and precision.
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- X. Chen, J. Zhu, Q. Xi and W. Yang, Sens. Actuators B: Chem., 161, 648 (2012); https://doi.org/10.1016/j.snb.2011.10.085.
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References
X. Chen, J. Zhu, Q. Xi and W. Yang, Sens. Actuators B: Chem., 161, 648 (2012); https://doi.org/10.1016/j.snb.2011.10.085.
P.R. May, Ph.D. Thesis, Relationship Knowledge and Parents Attitude Parents Behavior in Provision of Heat-Lowering Drugs (Antipyretics) in Infants Age (0-1 Year), University of Muhammadiyah Malang, Malang, Indonesia (2012).
J.M. Wilson, J.T. Slattery, A.J. Forte and S.D. Nelson, J. Chromatogr. B Biomed. Sci. Appl., 227, 453 (1982); https://doi.org/10.1016/S0378-4347(00)80398-9.
H.Ch. Curtius, M. Wolfensberger, B. Steinmann, U. Redweik and J. Siegfried, J. Chromatogr. A, 99, 529 (1974); https://doi.org/10.1016/S0021-9673(00)90882-3.
M. Maminski, M. Olejniczak, M. Chudy, A. Dybko and Z. Brzózka, Anal. Chim. Acta, 540, 153 (2005); https://doi.org/10.1016/j.aca.2004.09.011.
M.A. Tri, Master Thesis, Modification of Glassy Carbon and Graphite by Iridium Oxide Electrodeposition Technique for Application as Mercury Sensor Electrode, Department of Chemistry. Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Indonesia, Jawa Barat, Indonesia (2006).
A.A. Balandin, S. Ghosh, W.Z. Bao, I. Calizo, D. Teweldebrhan, F. Miao and C.N. Lau, Nano Lett., 8, 902 (2008); https://doi.org/10.1021/nl0731872.
M.D. Stoller, S.J. Park, Y.W. Zhu, J.H. An and R.S. Ruoff, Nano Lett., 8, 3498 (2008); https://doi.org/10.1021/nl802558y.
L. Marcinauskas, R. Kezelis, Z. Kavaliauskas, A. Zunda and M. Milieska, Roman. J. Phys., 62, 605 (2017).
Q. Jiang, M.Z. Qu, G.M. Zhou, B.L. Zhang and Z.L. Yu, Mater. Lett., 57, 988 (2002); https://doi.org/10.1016/S0167-577X(02)00911-4.
Y.-R. Huang, P.-H. Chuang and C.-L. Chen, Int. J. Heat Mass Transfer, 91, 45 (2015); https://doi.org/10.1016/j.ijheatmasstransfer.2015.07.110.
D.C. Marcano, D.V. Kosynkin, J.M. Berlin, A. Sinitskii, Z. Sun, A. Slesarev, L.B. Alemany, W. Lu and J.M. Tour, ACS Nano, 4, 4806 (2010); https://doi.org/10.1021/nn1006368.
L.T. Sutayasa and I.G.M. Sanjaya, UNESA J. Chem., 23-27 (2016).
D.A. Skoog, D.M. West, J.F. Holler and S.R. Crouch, Fundamentals of Analytical Chemistry, David Harris, Belmont: USA, edn 8 (2004).
S. Cheemalapati, S. Palanisamy and S.M. Chen, Int. J. Electrochem. Sci., 8, 3953 (2013).
S. Cheemalapati, S. Palanisamy, V. Mani and S.-M. Chen, Talanta, 117, 297 (2013); https://doi.org/10.1016/j.talanta.2013.08.041.
X. Kang, J. Wang, H. Wu, J. Liu, I.A. Aksay and Y. Lin, Talanta, 81, 754 (2010); https://doi.org/10.1016/j.talanta.2010.01.009.